Takes place in London, as various jewel heists baffle Scotland Yard, and a beautiful singer named Red gets framed as the culprit. A situation of this magnitude calls for drastic action, and soon the legendary Sherlock Homes hits the beat, with Dr. Watson and Tom and Jerry in tow. But the case grows even more challenging when Tom and Jerry resort to their old crazy tricks and games with one another. Favorite supporting characters from the original Tom and Jerry series also turn up, including Droopy, Butch and Tuffy.Miss Red is being blackmailed. When she asks Sherlock Holmes for help, he connects her case to a series of jewel thefts and tells his assistant Jerry the Mouse to work with Red's butler Tom the Cat for the duration of this case.